Coexisting hurthle cell neoplasm and thyroid hormone resistance
نویسندگان
چکیده
منابع مشابه
Functional polymorphisms in antioxidant genes in Hurthle cell thyroid neoplasm - an association of GPX1 polymorphism and recurrent Hurthle cell thyroid carcinoma
BACKGROUND Hurthle cells of the thyroid gland are very rich in mitochondria and oxidative enzymes. As a high level oxidative metabolism may lead to higher level of oxidative stress and can be associated with an increased risk for cancer, we investigated whether common functional polymorphisms in antioxidant genes (SOD2, CAT, GPX, GSTP1, GSTM1 and GSTT1) are associated with the development or cl...
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Thyroid fine-needle aspiration (FNA) is a standard procedure for the clinical triage of thyroid nodules. The diagnosis of an adequately sampled thyroid FNA is generally grouped into three categories: benign, malignant, and indeterminate. The latter group usually includes follicular neoplasm, follicular lesion, and sometimes a more specific diagnosis such as Hurthle cell neoplasm or follicular l...
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Giant pedunculated liposarcoma of the esophagus is considered a rare entity. They impose difficulties in management, especially the surgical approach. We report a case of giant pedunculated liposarcoma of the esophagus in a 62-year-old male who underwent cervical excision of this large tumor, and made a full recovery. Hurthle cell thyroid cancer was found during the work-up, which was managed a...
متن کامل[Thyroid hormone resistance syndromes].
Thyroid hormone resistance syndromes are a group of genetic conditions characterized by decreased tissue sensitivity to thyroid hormones. Three syndromes, in which resistance to hormone action is respectively due to mutations in the gene encoding for thyroid hormone receptor TRβ, impaired T4 and T3 transport, and impaired conversion of T4 to T3 mediated by deiodinases. An updated review of each...
متن کاملThyroid hormone resistance.
Thyroid hormone resistance (THR) is a rare syndrome of reduced end organ sensitivity. Patients with THR have elevated serum free thyroxine (FT4), free triiodothyronine (FT3), but normal or slightly elevated serum thyrotropin values. The characteristic clinical feature is goitre without symptoms and metabolic consequences of thyroid hormone excess. THR can be classified on the basis of tissue re...
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ژورنال
عنوان ژورنال: Endocrine Abstracts
سال: 2014
ISSN: 1479-6848
DOI: 10.1530/endoabs.35.p263